Pavel RÖSSNER, Jr., PhD.
Institute of Experimental Medicine AS CR, v.v.i., Prague, Czech Republic, EU
Position: Head of Laboratory of Genomics, Department of Genetic Ecotoxicology, Institute of Experimental Medicine AS CR, v.v.i., Prague, Czech Republic, EU
Specialization: In vitro and in vivo toxicology of nanoparticles and particulate matter of larger size, their effects on human health
At the NANOCON 2014 conference Dr. Pavel Rössner will deliver the invited lecture
at the thematic session D – Health, Safety and Environment Challenges.
Education and Career Accomplishments:
Pavel Rössner, Jr. (* 1971) received his PhD. in tumor immunology at the Institute of Molecular Genetics AS CR, v.v.i., Prague, Czech Republic, EU. At the Institute of Experimental Medicine AS CR, v.v.i., Prague, Czech Republic, EU he started his studies focusing on the effect of air pollutants on human health. During his postdoctoral training in the Department of Environmental Health Sciences, Columbia University, New York, USA (2003-2005) he concentrated on the role of oxidative damage, genetic polymorphisms and mutations in p53 on breast cancer risk and survival. After his return to the Institute of Experimental Medicine he concentrates on the role of air pollutants in the induction of oxidative damage to DNA, lipids and proteins, DNA repair response, and gene expression in environmentally-exposed populations. He further studies the effect of environmental pollution on pregnancy outcomes and children health. He also focuses on in vitro studies of effects of polycyclic aromatic hydrocarbons and particulate matter on biomarkers of oxidative stress, DNA repair and gene expression in model cell lines. In 2013 he received an ECNIS2 Fellowship to support his stay at the Department of Cancer Studies and Department of Genetics, University of Leicester, UK, EU. Since 2009 he is the head of the Laboratory of Genomics in the Department of Genetic Ecotoxicology at the Institute of Experimental Medicine AS CR, v.v.i., Prague, Czech Republic, EU.
Pavel Rössner, Jr. is currently involved in several projects in nanotoxicology including “Centre for studies on toxicity of nanoparticles” supported by the Czech Science Foundation and NANOSTOX, the project supported by the Czech Ministry of Education within the COST action MODENA. His research is mostly focused on genotoxic effects of nanoparticles on oxidative stress parameters, including oxidative damage to DNA, lipids and proteins.
Summary of publication activity:
- 51 articles in peer-reviewed journals, over 750 citations, H-index 16
- 2 chapters in books, guest editor of a special issue of Oxidative Medicine and Cellular Longevity
- Novotna, B., Jendelova, P., Kapcalova, M., Rossner, P., Jr., Turnovcova, K., Bagryantseva, Y., Babic, M., Horak, D., and Sykova, E. (2012) Oxidative damage to biological macromolecules in human bone marrow mesenchymal stromal cells labeled with various types of iron oxide nanoparticles. Toxicology Letters, 210, 53-63.